Applicants belonging to groups that have been traditionally underrepresented in biomedical research are strongly encouraged to apply. This includes: Individuals from underrepresented racial or ethnic groups. OR Individuals with disabilities, who are defined as those with a physical or mental impairment that substantially limits one or more major life activities. OR Individuals from disadvantaged backgrounds such as family annual income below established low-income thresholds, or an educational environment that has inhibited the individual from obtaining the knowledge, skills, and abilities necessary to develop and participate in a research career. To be considered for acceptance in UM-SMART, applicants must: - Be a current undergraduate student (completed sophomore year by June 1). We do not accept students who are applying to medical or graduate school for possible admission during the same year of participation in this program - Be a US citizen or permanent resident of the United States. - Have completed a physiology, biology, biochemistry or organic chemistry course, preferably with lab. - Have at least 100 hours of experience in a research lab by the summer of participation. (This is in addition to completing a lab associated with a science course.) - Submit two letters of recommendation, one of which must be from a research mentor or the instructor of a laboratory course. - Maintain a 3.2 cumulative grade point average or above. - Show proof of health insurance.